Institut Pasteur de Madagascar: Mapping and modeling the distribution and dynamics of mosquito vectors of arboviruses and the inherent disease risks in Madagascar

This project aims to better understand the environmental and climatic drivers affecting the transmission of Rift Valley fever and West Nile viruses (RVFV and WNV) by developing distribution and dynamic models of vectors and viruses across Madagascar 1\. Field collections of mosquitoes will be carried out bi- monthly in 75 biotopes located in 25 districts covering the 5 bioclimatic regions of Madagascar during one year. Environmental and climatic factors that influence patterns of mosquito diversity, abundance, feeding and sheltering behaviors will be analysed. Two further trapping campaigns (both in the dry and rainy season) will be set up for model validation. 2\. An innovative surveillance method consisting in the molecular detectionof RVFV and WNV on FTA®sugar-baited cards collected every 15 days will be carried out during one year. In bioclimatic regions where a positive result will be found on FTA cards, mosquitoes will be screened for the corresponding viruses. 3\. Both dynamic and distribution models of vectors and viruses will be developed and validated. Combining information on distributions and dynamics of vectors and viruses with host distributions, will enable mapping transmission risk for the two diseases.

Programme: International Training Fellowship

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